Pub. Date : 2012 Jul 7
PMID : 22579953
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines. | Prodigiosin | RAD51 recombinase | Homo sapiens |
| 2 | In addition, prodigiosin triggered phosphorylation of JNK and p38 MAPK, while pharmacological inhibition of JNK or p38 MAPK attenuated prodigiosin-mediated inhibition of RAD51 mRNA expression. | Prodigiosin | RAD51 recombinase | Homo sapiens |
| 3 | In addition, prodigiosin triggered phosphorylation of JNK and p38 MAPK, while pharmacological inhibition of JNK or p38 MAPK attenuated prodigiosin-mediated inhibition of RAD51 mRNA expression. | Prodigiosin | RAD51 recombinase | Homo sapiens |
| 4 | Lastly, cells with enforced RAD51 expression showed increased resistance to prodigiosin-induced cytotoxicity as well as inhibition of colony formation. | Prodigiosin | RAD51 recombinase | Homo sapiens |