Title : Copper chaperone antioxidant protein1 is essential for copper homeostasis.

Pub. Date : 2012 Jul

PMID : 22555879






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Copper chaperone antioxidant protein1 is essential for copper homeostasis. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
2 The shoot and root growth of atx1 and cchatx1 but not cch was specifically hypersensitive to excess Cu but not excess iron, zinc, or cadmium. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
3 The activities of antioxidant enzymes in atx1 and cchatx1 were markedly regulated in response to excess Cu, which confirms the phenotype of Cu hypersensitivity. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
4 The activities of antioxidant enzymes in atx1 and cchatx1 were markedly regulated in response to excess Cu, which confirms the phenotype of Cu hypersensitivity. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
5 Overexpression of ATX1 not only enhanced Cu tolerance and accumulation in excess Cu conditions but also tolerance to Cu deficiency. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
6 Overexpression of ATX1 not only enhanced Cu tolerance and accumulation in excess Cu conditions but also tolerance to Cu deficiency. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
7 In addition, the Cu-binding motif MXCXXC of ATX1 was required for these physiological functions. Copper homolog of anti-oxidant 1 Arabidopsis thaliana
8 In this study, we demonstrate that ATX1 plays an essential role in Cu homeostasis in conferring tolerance to excess Cu and Cu deficiency. Copper homolog of anti-oxidant 1 Arabidopsis thaliana