Title : The UGT1A3*2 polymorphism affects atorvastatin lactonization and lipid-lowering effect in healthy volunteers.

Pub. Date : 2012 Aug

PMID : 22555810






3 Functional Relationships(s)
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1 The UGT1A3*2 polymorphism affects atorvastatin lactonization and lipid-lowering effect in healthy volunteers. Atorvastatin UDP glucuronosyltransferase family 1 member A3 Homo sapiens
2 OBJECTIVE: We investigated whether the UGT1A3 polymorphisms play an important role in interindividual variations in atorvastatin lactonization and lipid-lowering effect. Atorvastatin UDP glucuronosyltransferase family 1 member A3 Homo sapiens
3 CONCLUSION: The UGT1A3*2 polymorphism is correlated with increased atorvastatin lactonization and may affect its lipid-lowering effect. Atorvastatin UDP glucuronosyltransferase family 1 member A3 Homo sapiens