Pub. Date : 2012 Aug
PMID : 22555810
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The UGT1A3*2 polymorphism affects atorvastatin lactonization and lipid-lowering effect in healthy volunteers. | Atorvastatin | UDP glucuronosyltransferase family 1 member A3 | Homo sapiens |
2 | OBJECTIVE: We investigated whether the UGT1A3 polymorphisms play an important role in interindividual variations in atorvastatin lactonization and lipid-lowering effect. | Atorvastatin | UDP glucuronosyltransferase family 1 member A3 | Homo sapiens |
3 | CONCLUSION: The UGT1A3*2 polymorphism is correlated with increased atorvastatin lactonization and may affect its lipid-lowering effect. | Atorvastatin | UDP glucuronosyltransferase family 1 member A3 | Homo sapiens |