Title : Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.

Pub. Date : 2012 Jul 15

PMID : 22552933






1 Functional Relationships(s)
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1 In 5/6Nx rats, the administration of nicotine significantly increased urinary protein excretion (onefold), worsened the glomerular injury score and increased fibronectin (~ 50%), NADPH oxidase 4 (NOX4; ~100%), and transforming growth factor-beta expression (~200%). Nicotine fibronectin 1 Rattus norvegicus