Title : 11-Oxoaerothionin isolated from the marine sponge Aplysina fistularis shows anti-inflammatory activity in LPS-stimulated macrophages.

Pub. Date : 2012 Dec

PMID : 22537094






1 Functional Relationships(s)
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1 When RAW264.7 cells and primary macrophages were preincubated with 11-oxoaerothionin and stimulated with LPS (lipopolysaccharide), a concentration-dependent inhibition of iNOS(inducible nitric oxide synthase) protein and NO(2)(-) (Nitrite) production were observed. Nitrites nitric oxide synthase 2, inducible Mus musculus