Title : Mono-(2-ethylhexyl) phthalate affects the steroidogenesis in rat Leydig cells through provoking ROS perturbation.

Pub. Date : 2012 Sep

PMID : 22525294






2 Functional Relationships(s)
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Protein Name
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1 Low concentrations of MEHP (20-200muM) provoked ROS perturbation and caused the stimulation of steroidogenic acute regulatory (StAR), cytochrome P450 side-chain cleavage (P450scc), 3beta-hydroxysteroid dehydrogenases (3beta-HSD) and 17beta-hydroxysteroid dehydrogenases (17beta-HSD) activities which elevated T production of ALCs. mono-(2-ethylhexyl)phthalate hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Rattus norvegicus
2 Low concentrations of MEHP (20-200muM) provoked ROS perturbation and caused the stimulation of steroidogenic acute regulatory (StAR), cytochrome P450 side-chain cleavage (P450scc), 3beta-hydroxysteroid dehydrogenases (3beta-HSD) and 17beta-hydroxysteroid dehydrogenases (17beta-HSD) activities which elevated T production of ALCs. mono-(2-ethylhexyl)phthalate hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Rattus norvegicus