Title : Prokaryotic selectivity and LPS-neutralizing activity of short antimicrobial peptides designed from the human antimicrobial peptide LL-37.

Pub. Date : 2012 Jun

PMID : 22521196






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To develop novel antimicrobial peptides (AMPs) with shorter lengths, improved prokaryotic selectivity and retained lipolysaccharide (LPS)-neutralizing activity compared to human cathelicidin AMP, LL-37, a series of amino acid-substituted analogs based on IG-19 (residues 13-31 of LL-37) were synthesized. Adenylyl sulfate cathelicidin antimicrobial peptide Homo sapiens