Title : Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.

Pub. Date : 2012 Apr 20

PMID : 22520755






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Although DOCK2 does not contain Dbl homology domain typically found in guanine nucleotide exchange factors, DOCK2 mediates the GTP-GDP exchange reaction for Rac through its DHR-2 domain. Guanosine Triphosphate AKT serine/threonine kinase 1 Homo sapiens