Pub. Date : 2012 Jul 1
PMID : 22517358
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Endogenously, H(2)S is produced as a metabolite of homocysteine (Hcy) by cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST). | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |
2 | Endogenously, H(2)S is produced as a metabolite of homocysteine (Hcy) by cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST). | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |
3 | Endogenously, H(2)S is produced as a metabolite of homocysteine (Hcy) by cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST). | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |
4 | Endogenously, H(2)S is produced as a metabolite of homocysteine (Hcy) by cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST). | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |
5 | Ex vivo renal artery culture with CBS, CSE, and 3MST triple gene therapy generated more H(2)S in the presence of Hcy, and these arteries were more responsive to endothelial-dependent vasodilation compared with nontransfected arteries treated with high Hcy. | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |
6 | We conclude that conversion of Hcy to H(2)S by CBS, CSE, or 3MST triple gene therapy improves renovascular function in HHcy. | Homocysteine | mercaptopyruvate sulfurtransferase | Homo sapiens |