Title : The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer.

Pub. Date : 2012 Aug

PMID : 22513004






7 Functional Relationships(s)
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1 Functional studies, conducted primarily on lipocalin 2 (Lcn2), the mouse homologue of human NGAL have revealed that Lcn2 has a strong affinity for iron complexed to both bacterial siderophores (iron-binding proteins) and certain human proteins like norepinephrine. Iron lipocalin 2 Homo sapiens
2 Functional studies, conducted primarily on lipocalin 2 (Lcn2), the mouse homologue of human NGAL have revealed that Lcn2 has a strong affinity for iron complexed to both bacterial siderophores (iron-binding proteins) and certain human proteins like norepinephrine. Iron lipocalin 2 Homo sapiens
3 Functional studies, conducted primarily on lipocalin 2 (Lcn2), the mouse homologue of human NGAL have revealed that Lcn2 has a strong affinity for iron complexed to both bacterial siderophores (iron-binding proteins) and certain human proteins like norepinephrine. Iron lipocalin 2 Homo sapiens
4 Functional studies, conducted primarily on lipocalin 2 (Lcn2), the mouse homologue of human NGAL have revealed that Lcn2 has a strong affinity for iron complexed to both bacterial siderophores (iron-binding proteins) and certain human proteins like norepinephrine. Iron lipocalin 2 Homo sapiens
5 By sequestering iron-laden siderophores, Lcn2 deprives bacteria of a vital nutrient and thus inhibits their growth (bacteriostatic effect). Iron lipocalin 2 Homo sapiens
6 By transporting iron into and out of the cell, NGAL also regulates iron responsive genes. Iron lipocalin 2 Homo sapiens
7 By transporting iron into and out of the cell, NGAL also regulates iron responsive genes. Iron lipocalin 2 Homo sapiens