Title : Impacts of dystrophin and utrophin domains on actin structural dynamics: implications for therapeutic design.

Pub. Date : 2012 Jun 29

PMID : 22504225






1 Functional Relationships(s)
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1 We previously used TPA to show that both dystrophin and utrophin have a paradoxical effect on actin rotational dynamics-restricting amplitude while increasing rate, thus increasing resilience, with utrophin more effective than dystrophin. Tetradecanoylphorbol Acetate dystrophin, muscular dystrophy Mus musculus