Title : Phosphatidylinositol 3-kinase-binding protein, PI3KAP/XB130, is required for cAMP-induced amplification of IGF mitogenic activity in FRTL-5 thyroid cells.

Pub. Date : 2012 Jun

PMID : 22496359






1 Functional Relationships(s)
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1 Addition of Src family kinase inhibitors, PP1 or PP2, during cAMP treatment abolished tyrosine phosphorylation of PI3KAP/XB130 and its interaction with p85 PI3K. Tyrosine SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus