Title : Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer.

Pub. Date : 2012 Aug

PMID : 22476852






1 Functional Relationships(s)
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1 We demonstrated that inhibition of mTORC1/2 by mTOR kinase inhibitors PP242 and OSI-027 effectively suppress phosphorylation of Akt (S473) and breast cancer cell proliferation. OSI 027 CREB regulated transcription coactivator 1 Mus musculus