Pub. Date : 2012 Aug
PMID : 22445862
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Docetaxel and 5-fluorouracil induce human p53 tumor suppressor gene transcription via a short sequence at core promoter element. | Docetaxel | tumor protein p53 | Homo sapiens |
| 2 | Docetaxel (DOC), a member of the taxanes family that is widely used in cancer chemotherapy, activates p53 at the transcriptional level. | Docetaxel | tumor protein p53 | Homo sapiens |
| 3 | Docetaxel (DOC), a member of the taxanes family that is widely used in cancer chemotherapy, activates p53 at the transcriptional level. | Docetaxel | tumor protein p53 | Homo sapiens |
| 4 | We demonstrated that p53 is induced by low dose DOC treatment, resulting in MDR-1 gene suppression in human lung cancer cells. | Docetaxel | tumor protein p53 | Homo sapiens |