Title : Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7α1 in the liver of weaning piglets.

Pub. Date : 2012 Dec

PMID : 22444501






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1 These results indicate that maternal low-protein diet during gestation and lactation affects hepatic cholesterol metabolism in weaning piglets by modifying the epigenetic regulation of HMGCR and CYP7alpha1 genes, which implicates possible long-term consequences in cholesterol homeostasis later in adult life. Cholesterol 3-hydroxy-3-methylglutaryl-CoA reductase Sus scrofa