Pub. Date : 2012 Mar 21
PMID : 22442074
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Finally, the depressive-like behaviors in BDNF(+/Met) mice could be selectively rescued by acute administration of desipramine but not fluoxetine. | Desipramine | brain derived neurotrophic factor | Mus musculus | ||
| 2 | Importantly, desipramine but not fluoxetine has antidepressant effects on BDNF(+/Met) mice, suggesting that specific classes of antidepressant may be a more effective treatment option for depressive symptoms in humans with this genetic variant BDNF. | Desipramine | brain derived neurotrophic factor | Mus musculus | ||