Title : Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1,2-dimethylhydrazine-instigated colon preneoplastic lesions in rats.

Pub. Date : 2012 Apr 11

PMID : 22439659






1 Functional Relationships(s)
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1 Subcutaneous injection of DMH (40 mg/kg body weight twice a week for 2 weeks) to the rats resulted in elevated expression of ODC, a genetic marker for CRC, and its transcription factor myelocytomatosis oncogene (c-myc). 1,2-Dimethylhydrazine ornithine decarboxylase 1 Rattus norvegicus