Pub. Date : 2012 May
PMID : 22438365
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EAE was induced in SJL mice by using proteolipid protein (PLP), and mice were treated with either 4-aminobenzoic acid hydrazide (ABAH), 40 mg/kg injected intraperitoneally, an irreversible inhibitor of MPO, or saline as control, and followed up to day 40 after induction. | 4-aminobenzhydrazide | myeloperoxidase | Mus musculus |
| 2 | Inhibiting MPO activity with ABAH resulted in decrease in MPO-Gd-positive lesion volume (P = .012), number (P = .009), and enhancement intensity (P = .03) at MR imaging, reflecting lower local MPO activity (P = .03), compared with controls. | 4-aminobenzhydrazide | myeloperoxidase | Mus musculus |
| 3 | Inhibiting MPO activity with ABAH resulted in decrease in MPO-Gd-positive lesion volume (P = .012), number (P = .009), and enhancement intensity (P = .03) at MR imaging, reflecting lower local MPO activity (P = .03), compared with controls. | 4-aminobenzhydrazide | myeloperoxidase | Mus musculus |
| 4 | Inhibiting MPO activity with ABAH resulted in decrease in MPO-Gd-positive lesion volume (P = .012), number (P = .009), and enhancement intensity (P = .03) at MR imaging, reflecting lower local MPO activity (P = .03), compared with controls. | 4-aminobenzhydrazide | myeloperoxidase | Mus musculus |