Title : Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells.

Pub. Date : 2012

PMID : 22427795






5 Functional Relationships(s)
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1 Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells. Adenosine Triphosphate solute carrier family 25 member 27 Homo sapiens
2 Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells. Adenosine Triphosphate solute carrier family 25 member 27 Homo sapiens
3 Increased ATP supply was observed in UCP4-overexpressing cells compared to controls (p<0.05). Adenosine Triphosphate solute carrier family 25 member 27 Homo sapiens
4 Our findings elucidate how UCP4 overexpression increases ATP synthesis by specifically interacting with Complex II. Adenosine Triphosphate solute carrier family 25 member 27 Homo sapiens
5 This highlights a unique role of UCP4 as a potential regulatory target to modulate mitochondrial Complex II and ATP output in preserving existing neurons against energy crisis. Adenosine Triphosphate solute carrier family 25 member 27 Homo sapiens