Pub. Date : 2012 Jun
PMID : 22426850
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cerulenin-induced apoptosis is mediated by disrupting the interaction between AIF and hexokinase II. | Cerulenin | hexokinase 2 | Homo sapiens |
| 2 | Here, we showed that cerulenin disrupts the physical association between HKII and AIF, leading to eventual cell death. | Cerulenin | hexokinase 2 | Homo sapiens |
| 3 | Collectively, cerulenin induces apoptosis via disrupting the interaction between AIF and HKII and inhibition of PI3K sensitizes cells to cerulenin-induced apoptosis in ZR-75-1 cells. | Cerulenin | hexokinase 2 | Homo sapiens |