Title : Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus.

Pub. Date : 2012 Mar 18

PMID : 22426352






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mice deficient in the peroxisomal enzyme glyceronephosphate O-acyltransferase (GNPAT), essential for the synthesis of ether lipids, had significant alteration of the thymic maturation of iNKT cells and fewer iNKT cells in both thymus and peripheral organs, which confirmed the role of ether-bonded lipids as iNKT cell antigens. ether lipids glyceronephosphate O-acyltransferase Mus musculus