Pub. Date : 2012 Jul
PMID : 22411600
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with AT-101 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of breast cancer cells by inducing death receptors 4 and 5 protein levels. | gossypol acetic acid | TNF superfamily member 10 | Homo sapiens |
| 2 | Pretreatment with AT-101 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of breast cancer cells by inducing death receptors 4 and 5 protein levels. | gossypol acetic acid | TNF superfamily member 10 | Homo sapiens |
| 3 | CONCLUSIONS: These findings all together, strongly suggest that pretreatment with AT-101 enhances TRAIL-induced death-inducing signaling complex resulting in the engagement of the mitochondrial pathway to apoptosis in breast cancer cells. | gossypol acetic acid | TNF superfamily member 10 | Homo sapiens |