Pub. Date : 2012 Mar 30
PMID : 22402285
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences. | Tyrosine | carbamoyl-phosphate synthetase 1 | Mus musculus |
| 2 | The decreased CPS1 activity was not recovered by treatment with reduced glutathione, suggesting that the decrease of the CPS1 activity is due to tyrosine nitration rather than cysteine oxidation. | Tyrosine | carbamoyl-phosphate synthetase 1 | Mus musculus |
| 3 | The decreased CPS1 activity was not recovered by treatment with reduced glutathione, suggesting that the decrease of the CPS1 activity is due to tyrosine nitration rather than cysteine oxidation. | Tyrosine | carbamoyl-phosphate synthetase 1 | Mus musculus |
| 4 | LC-MS analysis of in-gel digested samples, and a Popitam-based modification search located 5 out of 36 tyrosine residues in CPS1 that were nitrated. | Tyrosine | carbamoyl-phosphate synthetase 1 | Mus musculus |
| 5 | In conclusion, this study demonstrated the tyrosine nitration of CPS1 by peroxynitrite and its functional consequence. | Tyrosine | carbamoyl-phosphate synthetase 1 | Mus musculus |