Title : 5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis.

Pub. Date : 2012 Jul

PMID : 22398368






1 Functional Relationships(s)
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1 In particular, we found that drug treatment led to substantially reduced expression of farnesyl diphosphate synthase (FDPS) and farnesyl diphosphate farnesyltransferase (FDFT1), two important enzymes involved in de novo cholesterol synthesis. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens