Title : Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration.

Pub. Date : 2012 May 1

PMID : 22394507






2 Functional Relationships(s)
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1 Interestingly, quercetin also modulated the expression of two target genes regulated by STAT3, i.e. cyclin D1 and matrix metalloproteinase-2 (MMP-2). Quercetin cyclin D1 Homo sapiens
2 Moreover, quercetin reduced the recruitment of STAT3 at the cyclin D1 promoter and inhibited Rb phosphorylation in the presence of IL-6. Quercetin cyclin D1 Homo sapiens