Title : Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts.

Pub. Date : 2012

PMID : 22393274






4 Functional Relationships(s)
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Compound Name
Protein Name
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1 Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts. halofuginone transforming growth factor beta 1 Homo sapiens
2 PURPOSE: Due to its ability to disrupt transforming growth factor beta (TGF-beta) signaling, halofuginone has been successfully used to treat various fibrotic disorders. halofuginone transforming growth factor beta 1 Homo sapiens
3 PURPOSE: Due to its ability to disrupt transforming growth factor beta (TGF-beta) signaling, halofuginone has been successfully used to treat various fibrotic disorders. halofuginone transforming growth factor beta 1 Homo sapiens
4 TGF-beta was used to stimulate pro-fibrotic responses from corneal fibroblasts under halofuginone treatment. halofuginone transforming growth factor beta 1 Homo sapiens