Title : Early effect of tacrolimus in improving excitation-contraction coupling in myasthenia gravis.

Pub. Date : 2012 Sep

PMID : 22386321






4 Functional Relationships(s)
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1 Besides immunosuppression, tacrolimus has been reported to have the potential to increase muscle strength by enhancing ryanodine receptor (RyR) function. Tacrolimus ryanodine receptor 1 Homo sapiens
2 Besides immunosuppression, tacrolimus has been reported to have the potential to increase muscle strength by enhancing ryanodine receptor (RyR) function. Tacrolimus ryanodine receptor 1 Homo sapiens
3 However, few attempts have been made to demonstrate the early effect of tacrolimus as an RyR enhancer in clinical investigation. Tacrolimus ryanodine receptor 1 Homo sapiens
4 SIGNIFICANCE: This early effect of tacrolimus may imply a pharmacological enhancement of RyR function to improve E-C coupling in MG. Tacrolimus ryanodine receptor 1 Homo sapiens