Pub. Date : 2012 Jun
PMID : 22383427
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways. | Sorafenib | androgen receptor | Homo sapiens |
| 2 | Most interestingly, we show that sorafenib has an inhibitory effect on androgen receptor (AR) and prostate-specific antigen expression. | Sorafenib | androgen receptor | Homo sapiens |
| 3 | Most interestingly, we show that sorafenib has an inhibitory effect on androgen receptor (AR) and prostate-specific antigen expression. | Sorafenib | androgen receptor | Homo sapiens |
| 4 | In cells in which AR expression was downregulated by short interfering RNA, the treatment with sorafenib increased apoptosis in an additive manner. | Sorafenib | androgen receptor | Homo sapiens |