Pub. Date : 2012 Mar
PMID : 22382998
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | "Regulator of G-protein Signaling" (RGS) proteins constitute a class of intracellular signaling regulators that accelerate GTP hydrolysis by heterotrimeric Galpha subunits. | Guanosine Triphosphate | paired like homeodomain 2 | Homo sapiens |
| 2 | "Regulator of G-protein Signaling" (RGS) proteins constitute a class of intracellular signaling regulators that accelerate GTP hydrolysis by heterotrimeric Galpha subunits. | Guanosine Triphosphate | paired like homeodomain 2 | Homo sapiens |
| 3 | Described in this unit are high-throughput screening procedures for identifying modulators of RGS protein-mediated GTPase acceleration (GAP activity), for assessment of RGS domain/Galpha interactions (most avid in vitro when Galpha is bound by aluminum tetrafluoride), and for validation of candidate GAP-modulatory molecules with the single-turnover GTP hydrolysis assay. | Guanosine Triphosphate | paired like homeodomain 2 | Homo sapiens |