Title : Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.

Pub. Date : 2012 Apr 13

PMID : 22375014






1 Functional Relationships(s)
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1 We found that Tdp1-/- cells were not only hypersensitive to camptothecin and bleomycin but also to etoposide, methyl methanesulfonate (MMS), H(2)O(2), and ionizing radiation. Camptothecin tyrosyl-DNA phosphodiesterase 1 Gallus gallus