Pub. Date : 2012 Mar 27
PMID : 22352884
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis. | Iron | frataxin | Homo sapiens |
| 2 | Human FXN is a component of the NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex and activates the cysteine desulfurase and Fe-S cluster biosynthesis reactions. | Iron | frataxin | Homo sapiens |
| 3 | Human FXN is a component of the NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex and activates the cysteine desulfurase and Fe-S cluster biosynthesis reactions. | Iron | frataxin | Homo sapiens |
| 4 | Human FXN is a component of the NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex and activates the cysteine desulfurase and Fe-S cluster biosynthesis reactions. | Iron | frataxin | Homo sapiens |
| 5 | Human FXN is a component of the NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex and activates the cysteine desulfurase and Fe-S cluster biosynthesis reactions. | Iron | frataxin | Homo sapiens |
| 6 | In contrast, the Escherichia coli FXN homologue CyaY inhibits Fe-S cluster biosynthesis. | Iron | frataxin | Homo sapiens |
| 7 | These data are consistent with a model in which the frataxin-less Fe-S assembly complex exists as a mixture of functional and nonfunctional states, which are stabilized by binding of frataxin homologues. | Iron | frataxin | Homo sapiens |
| 8 | These data are consistent with a model in which the frataxin-less Fe-S assembly complex exists as a mixture of functional and nonfunctional states, which are stabilized by binding of frataxin homologues. | Iron | frataxin | Homo sapiens |