Title : Immunoproteasome-specific inhibitors and their application.

Pub. Date : 2012

PMID : 22350900






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Immunoproteasomes (IPs) containing the interferon-inducible subunits beta1i (LMP2), beta2i (MECL-1), and beta5i (LMP7) alter proteasomal cleavage preference, optimise the generation of peptide ligands of MHC class I molecules, alter cytokine profile, influence T-helper cell differentiation, and play a role in T-cell survival. IPS proteasome 20S subunit beta 10 Homo sapiens
2 Immunoproteasomes (IPs) containing the interferon-inducible subunits beta1i (LMP2), beta2i (MECL-1), and beta5i (LMP7) alter proteasomal cleavage preference, optimise the generation of peptide ligands of MHC class I molecules, alter cytokine profile, influence T-helper cell differentiation, and play a role in T-cell survival. IPS proteasome 20S subunit beta 10 Homo sapiens