Title : cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane.

Pub. Date : 2012 Mar 6

PMID : 22343288






1 Functional Relationships(s)
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1 Furthermore, depletion of phosphatidic acid by inhibition of phospholipase D1 prevents cAMP-induced translocation of Epac1 as well as the subsequent activation of Rap at the plasma membrane. Phosphatidic Acids phospholipase D1 Homo sapiens