Title : Paclitaxel-hyaluronan hydrosoluble bioconjugate: mechanism of action in human bladder cancer cell lines.

Pub. Date : 2013 Oct

PMID : 22341413






1 Functional Relationships(s)
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1 RESULTS: The paclitaxel-hyaluronan bioconjugate bound to UC tumor cells entered intracellular compartments through a saturable and energy-dependent mechanism that involved CD44, as assessed by blocking with specific antibody. Paclitaxel CD44 molecule (Indian blood group) Homo sapiens