Title : Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.

Pub. Date : 2012 Apr 12

PMID : 22339362






1 Functional Relationships(s)
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1 This study describes the development of a novel class of dUTPase inhibitors based on the structure-activity relationship (SAR) studies of uracil derivatives. Uracil Deoxyuridine triphosphatase Drosophila melanogaster