Pub. Date : 2012 May 1
PMID : 22338016
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Akt inhibitors MK-2206 and nelfinavir overcome mTOR inhibitor resistance in diffuse large B-cell lymphoma. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Nelfinavir and MK-2206, chosen for their Akt-inhibitory properties, yielded synergistic inhibition of cell viability in combination with rapamycin in DLBCL cell lines, and potently inhibited phosphorylation of Akt and downstream targets of activated mTOR. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Nelfinavir and MK-2206, chosen for their Akt-inhibitory properties, yielded synergistic inhibition of cell viability in combination with rapamycin in DLBCL cell lines, and potently inhibited phosphorylation of Akt and downstream targets of activated mTOR. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |