Title : Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry.

Pub. Date : 2012 Jun

PMID : 22337655






1 Functional Relationships(s)
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1 A coupled fluorescent assay is described for mPGES-1 where PGH(2) is generated in situ using the action of cyclooxygenase 2 (Cox-2) on arachidonic acid. Prostaglandin H2 prostaglandin E synthase Mus musculus