Title : Effect of albumin on human liver microsomal and recombinant CYP1A2 activities: impact on in vitro-in vivo extrapolation of drug clearance.

Pub. Date : 2012 May

PMID : 22331994






1 Functional Relationships(s)
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1 Long-chain unsaturated fatty acids inhibit several cytochrome P450 and UDP-glucuronosyltransferase (UGT) enzymes involved in drug metabolism, including CYP2C8, CYP2C9, UGT1A9, UGT2B4, and UGT2B7. long-chain unsaturated fatty acids UDP glucuronosyltransferase family 2 member B4 Homo sapiens