Title : The potential of exploiting DNA-repair defects for optimizing lung cancer treatment.

Pub. Date : 2012 Feb 14

PMID : 22330686






1 Functional Relationships(s)
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1 Optimizing treatment according to tumor status for DNA-repair biomarkers, such as ERCC1, BRCA1 or RRM1, could predict response to platinum, taxanes and gemcitabine-based therapies, respectively, and might improve substantially the response of individual patients" tumors. Platinum ribonucleotide reductase catalytic subunit M1 Homo sapiens