Title : Amide analogues of CD1d agonists modulate iNKT-cell-mediated cytokine production.

Pub. Date : 2012 May 18

PMID : 22324848






1 Functional Relationships(s)
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1 All of the analogues were found to stimulate murine and human iNKT cells by CD1d-mediated presentation to varying degrees; however, the thioamide and carbamate analogues of ThrCer were of particular interest in that they elicited a strongly polarized cytokine response (more interferon-gamma (IFN-gamma), no interleukin-4 (IL-4)) in mice. thrcer CD1d molecule Homo sapiens