Title : TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.

Pub. Date : 2012 May 1

PMID : 22323359






2 Functional Relationships(s)
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1 TMPRSS6 polymorphisms were also associated with lower serum iron (SI) and hemoglobin levels, consistent with their associations to increased iron deficiency and anemia risk. Iron transmembrane serine protease 6 Homo sapiens
2 Our findings suggest that TF, TFR2 and TMPRSS6 polymorphisms are significantly associated with decreased iron status, but only variants in TMPRSS6 are genetic risk factors for iron deficiency and IDA. Iron transmembrane serine protease 6 Homo sapiens