Title : Enhancing CHK1 inhibitor lethality in glioblastoma.

Pub. Date : 2012 Apr

PMID : 22313687






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Multiple MEK1/2 inhibitors (CI-1040 (PD184352); AZD6244 (ARRY-142886)) interacted with multiple CHK1 inhibitors (UCN-01, AZD7762) to kill multiple primary human glioma cell isolates that have a diverse set of genetic alterations typically found in the disease. AZD 6244 mitogen-activated protein kinase kinase 1 Homo sapiens