Title : Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β.

Pub. Date : 2012 Feb 24

PMID : 22310719






1 Functional Relationships(s)
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1 The treatment of MDA-MB-231 cells with MG132 induced endoplasmic reticulum stress through the induction of ATF6a, PERK phosphorylation, and CHOP, and apoptosis through the cleavage of Bax and procaspase-3. benzyloxycarbonylleucyl-leucyl-leucine aldehyde caspase 3 Homo sapiens