Title : Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.

Pub. Date : 2012 Feb 7

PMID : 22308374






1 Functional Relationships(s)
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1 Here we report that reduction of the heme iron to the ferrous [Fe(II)] state in DGCR8 abolishes the pri-miRNA processing activity. Iron DGCR8 microprocessor complex subunit Homo sapiens