Title : Extracellular nucleotide inhibits cell proliferation and negatively regulates Toll-like receptor 4 signalling in human progenitor endothelial cells.

Pub. Date : 2012 Jul

PMID : 22299633






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When human EPCs were stimulated with LPS and nucleotides, ATP or UTP inhibited the expression of pro-inflammatory cytokines including MCP-1 (monocyte chemoattractant protein-1), IFNalpha (interferon alpha), TNFalpha (tumour necrosis factor alpha) and adhesion molecule VCAM-1 (vascular cell adhesion molecule 1) induced by LPS. Adenosine Triphosphate C-C motif chemokine ligand 2 Homo sapiens
2 When human EPCs were stimulated with LPS and nucleotides, ATP or UTP inhibited the expression of pro-inflammatory cytokines including MCP-1 (monocyte chemoattractant protein-1), IFNalpha (interferon alpha), TNFalpha (tumour necrosis factor alpha) and adhesion molecule VCAM-1 (vascular cell adhesion molecule 1) induced by LPS. Adenosine Triphosphate C-C motif chemokine ligand 2 Homo sapiens