Pub. Date : 2012 Apr
PMID : 22294162
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | N-acetylcysteine, a reactive oxygen species scavenger, not only blocked the oridonin-induced increase in hydrogen peroxide and glutathione depletion, but also blocked apoptosis and senescence induced by oridonin, as evidenced by the decrease in Annexin V and senescence-associated beta-galactosidase- positive cells and the inhibition of oridonin-induced upregulation of p53 and p16 and downregulation of c-Myc. | Acetylcysteine | tumor protein p53 | Homo sapiens |