Title : P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.

Pub. Date : 2012 Mar

PMID : 22283740






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The ROS scavenger N-acetyl cysteine (NAC) attenuated silibinin-induced up-regulation of p-p53 expression, suggesting that p53 might be regulated by ROS and forms a positive feedback loop with ROS. Acetylcysteine tumor protein p53 Homo sapiens
2 The ROS scavenger N-acetyl cysteine (NAC) attenuated silibinin-induced up-regulation of p-p53 expression, suggesting that p53 might be regulated by ROS and forms a positive feedback loop with ROS. Acetylcysteine tumor protein p53 Homo sapiens
3 The ROS scavenger N-acetyl cysteine (NAC) attenuated silibinin-induced up-regulation of p-p53 expression, suggesting that p53 might be regulated by ROS and forms a positive feedback loop with ROS. Acetylcysteine tumor protein p53 Homo sapiens
4 The ROS scavenger N-acetyl cysteine (NAC) attenuated silibinin-induced up-regulation of p-p53 expression, suggesting that p53 might be regulated by ROS and forms a positive feedback loop with ROS. Acetylcysteine tumor protein p53 Homo sapiens