Pub. Date : 2012 Mar 1
PMID : 22279108
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our previous in vitro studies suggested that exposure to the nicotine component of cigarette smoke skews the differentiation of both human and mouse dendritic cell (DC) precursors into atypical DCs (DCs differentiated ex vivo in the presence of nicotine) lacking parameters essential for the development of Th1-mediated immunity. | Nicotine | negative elongation factor complex member C/D, Th1l | Mus musculus |
| 2 | Our previous in vitro studies suggested that exposure to the nicotine component of cigarette smoke skews the differentiation of both human and mouse dendritic cell (DC) precursors into atypical DCs (DCs differentiated ex vivo in the presence of nicotine) lacking parameters essential for the development of Th1-mediated immunity. | Nicotine | negative elongation factor complex member C/D, Th1l | Mus musculus |
| 3 | In addition, DC subsets isolated from mice exposed to nicotine produced significantly less cytokines in response to Th1 adjuvants and inadequately supported the development of Ag-specific Th1 cells. | Nicotine | negative elongation factor complex member C/D, Th1l | Mus musculus |
| 4 | In addition, DC subsets isolated from mice exposed to nicotine produced significantly less cytokines in response to Th1 adjuvants and inadequately supported the development of Ag-specific Th1 cells. | Nicotine | negative elongation factor complex member C/D, Th1l | Mus musculus |