Title : Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration.

Pub. Date : 2012 Jan 23

PMID : 22270919






1 Functional Relationships(s)
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1 These data demonstrate that generation of PA downstream of DGK-alpha is essential to connect expression of mutant p53s or inhibition of alphavbeta3 to RCP and for this Rab11 effector to drive the trafficking of alpha5beta1 that is required for tumor cell invasion through three-dimensional matrices. Phosphatidic Acids RAB11A, member RAS oncogene family Homo sapiens