Title : Integrin-mediated membrane blebbing is dependent on sodium-proton exchanger 1 and sodium-calcium exchanger 1 activity.

Pub. Date : 2012 Mar 23

PMID : 22270364






2 Functional Relationships(s)
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1 However, inhibition of NCX1 enhances cell blebbing; cells become swollen because of NHE1 induced intracellular sodium accumulation. Sodium solute carrier family 9 member A1 Homo sapiens
2 Our study found that NHE1 induced sodium influx is a driving force for membrane bleb growth, while sodium efflux (and calcium influx) induced by NCX1 in a reverse mode results in membrane bleb retraction. Sodium solute carrier family 9 member A1 Homo sapiens